基于FLAC3D的桥台和坝体基础底面及地基应力分析研究

为了对桥台和坝体基础底面及地基应力进行研究，采用FLAC^3D数值模拟软件，分析了FLAC^3D数值模拟的计算过程，建立了桥坝三维实体几何模型，根据实际情况，对模型所使用材料物理力学性质以及模型的边界条件、上部结构对桥台的外荷载进行赋值研究，模拟分析了桥台和坝体基础底面应力。研究得出:随着桥台与坝体的各个阶段应力的施加，桥台基础底面拉应力主要集中在矩形四周，然而坝体的基础底面拉应力却主要集中在基底两侧，模拟分析混凝土的抗拉强度大于坝体与桥台基础底面最大拉应力，验证了基础强度满足要求。研究为类似工程条件下桥坝基础强度的验证提供一定的借鉴意义。     

On the Genesis of the Marshall-Olkin Family of Distributions via the T-<i>X</i> Family Approach: Statistical Modeling

In the last couple of years, there Has been an increased interest among the statisticians to define new families of distributions by adding one or more additional parameter(s) to the baseline distribution. In this regard, a number of families have been introduced and studied. One such example is the Marshall-Olkin family of distributions that is one of the most prominent approaches used to generalize the existing distributions. Whenever, we see a new method, the natural questions come in to mind are (i) what are the genesis of the newly proposed method and (ii) how did the proposed method is obtained. No doubt, the Marshall-Olkin family is a very useful method and has attracted the researchers. But, unfortunately, the authors failed to provide the explanation about the genesis of the method that how this family of distributions is obtained. To address this issue, in this article, an attempt Has been made to provide a straight forward computation about the genesis of the Marshall-Olkin family that somehow completes its derivation. The genesis of the Marshall-Olkin family is based on the T-X family approach. Furthermore, we have showed that other extensions of the Marshall-Olkin family can also be obtained via the T-X family method. Finally, a real-life application form insurance science is presented to illustrate the newly proposed extension of the Marshall-Olkin family.     

Effects of different agro-industrial waste as substrates on proximate composition,metals, and mineral contents of oyster mushroom (Pleurotus ostreatus)

The use of agro-industrial waste as substrates for mushroom cultivation is considered a promising management strategy for reducing and valorising these wastes, simultaneously reducing the cost of mushroom cultivation. In this study, oyster mushroom Pleurotus ostreatus were cultivated on twelve substrates composed of either tea waste, lime sawdust, alder sawdust, hornbeam sawdust/shaving, wheat stalk-straw, wheat bran or their composite to determine the proximate composition and accumulation of thirteen elements in their fruiting bodies. The proximate composition of P. ostreatus did not show a significant difference, regardless of the employed substrate. (one-way manova ; F_{(66, 107)} = 1.329, Wilk’s λ = 0.041, P > 0.05). However, their chemical element contents show a statistically significant difference (one-way manova ; F_{(132, 418)} = 32.163, Wilk’s λ = 0.000, P < 0.05). These results were supported by discriminant function and principal component analyses. The highest mean concentrations of six of twelve elements (i.e., Ca, Mg, Na, Zn, Cd and Cr) were recorded in P. ostreatus cultivated on the lime-sawdust substrate. Three health indices viz., estimated daily intake, target hazard quotient (THQ) and total THQ were applied to determine the risk to human health via the consumption of P. ostreatus, suggesting that they are safe for human consumption.     

Antibacterial activity and action target of phenyllactic acid against Staphylococcus aureus and its application in skim milk and cheese

Phenyllactic acid (PLA) has been demonstrated to possess antibacterial activity and capacity to prolong food shelf life. However, studies on the performance of PLA in inhibiting Staphylococcus aureus and its effectiveness when applied to dairy products are largely lacking. Here, antibacterial activity (planktonic and biofilm states) of PLA against S. aureus CICC10145 (S. aureus_45) were investigated. The results showed that PLA inhibited growth of S. aureus_45 and formation of S. aureus_45 biofilm. Next, the antibacterial action target of PLA was uncovered from both physiological and phenotypic perspectives. The results showed that PLA decreased cell metabolic activity and cell viability, damaged cell membrane integrity, triggered leakage of intracellular contents (DNA, proteins, and ATP), and caused oxidative stress damage and morphological deformation of S. aureus_45. In practical application, the antibacterial activity of PLA against S. aureus_45 cells was further confirmed in skim milk and cheese as dairy food models, and the antibacterial effects can be adequately maintained during storage for 21 d, at least at 4°C. These findings suggested that PLA could be a potential candidate for controlling S. aureus outgrowth in dairy foods.     

3-<i>epi</i>-bufotalin suppresses the proliferation in colorectal cancer cells through the inhibition of the JAK1/STAT3 signaling pathway

Traditional Chinese medicine (TCM) has been increasingly employed in the last decades in China for both preventing and treating a variety of cancers. 3-epi-bufotalin is an active ingredient of TCM “Chanpi” with anti-tumor potential. However, the effect and mechanism of 3-epi-bufotalin on colorectal cancers were not well disclosed. The present study demonstrated that 3-epi-bufotalin could reduce viability, trigger apoptosis, and block the cell cycle at the G₂/M stage in colorectal cancer cell lines HT29, RKO, and COLO205 in vitro. Moreover, 3-epi-bufotalin inhibited the JAK1/STAT3 signaling pathway. These results indicated the anti-proliferation ability of 3-epi-bufotalin in colorectal cancer cells.     

提高近红外视象管制靶工艺稳定性研究

根据近红外视象管特点,设计了专用的靶面蒸涂设备,改进了靶面加热方法、蒸发舟的形状以及工作气流的控制方法,确定了一种稳定性较好的工艺,使制靶成品率大大提高,整管成品率因此从过去的5%提高到30%。     

石油企业加强预算管理的途径和措施

针对油田企业预算管理存在的问题,阐述了加强预算管理的途径和措施:设置专门的预算管理机构,并建立预算工作岗位责任制;以油田企业战略为基础编制预算;设置弹性预算指标,建立预算预警机制和预算结果质询制度;适时调整、编制动态预算;采取有效的考核与激励措施,鼓励全员参与预算管理。     

浅析模糊评价方法在矿井安全管理中的应用

针对矿井安全管理中不同层次的考核指标,提出了科学的模糊评价模型,并结合实例说明其原理。该方法较好地反映了评价过程和评价因素的模糊性概念,为矿井安全管理提供了一种合理的途径。     

低惰性高分辨率的硒化镉摄像管靶面

介绍了一种改进了的硒化镉摄像管靶面,该靶面由光电导层硒化镉、氧化层硒酸镉、传输层及扫描阻挡层硫化锑组成。传输层独创性地采用了具有内建电场作用的非晶态As_2Se_3和高暗电阻率材料的非晶态As_1Se_9的复合结构,从而使靶面的惰性和分辨率得到了显著改善。比较详细地分析了这种靶面的工作原理,同时还介绍了制作这种靶面的工艺方法。